Cognitive diagnosis (CD) aims to reveal students' proficiency in specific knowledge concepts. With the increasing adoption of intelligent education applications, accurately assessing students' knowledge mastery has become an urgent challenge. Although existing cognitive diagnosis frameworks enhance diagnostic accuracy by analyzing students' explicit response records, they primarily focus on individual knowledge state, failing to adequately reflect the relative ability performance of students within hierarchies. To address this, we propose the Hierarchy Constraint-Aware Cognitive Diagnosis Framework (HCD), designed to more accurately represent student ability performance within real educational contexts. Specifically, the framework introduces a hierarchy mapping layer to identify students' levels. It then employs a hierarchy convolution-enhanced attention layer for in-depth analysis of knowledge concepts performance among students at the same level, uncovering nuanced differences. A hierarchy inter-sampling attention layer captures performance differences across hierarchies, offering a comprehensive understanding of the relationships among students' knowledge state. Finally, through personalized diagnostic enhancement, the framework integrates hierarchy constraint perception features with existing models, improving the representation of both individual and group characteristics. This approach enables precise inference of students' knowledge state. Research shows that this framework not only reasonably constrains changes in students' knowledge states to align with real educational settings, but also supports the scientific rigor and fairness of educational assessments, thereby advancing the field of cognitive diagnosis.

The safe and reliable operation of complex electromechanical systems in nuclear power plants is crucial for the safe production of nuclear power plants and their nuclear power unit. Therefore, accurate and timely fault diagnosis of nuclear power systems is of great significance for ensuring the safe and reliable operation of nuclear power plants. The existing fault diagnosis methods mainly target a single device or subsystem, making it difficult to analyze the inherent connections and mutual effects between different types of faults at the entire unit level. This article uses the AP1000 full-scale simulator to simulate the important mechanical component failures of some key systems in the primary and secondary circuits of nuclear power units, and constructs a fault dataset. Meanwhile, a hierarchical multi granularity classification fault diagnosis model based on the EfficientNet large model is proposed, aiming to achieve hierarchical classification of nuclear power faults. The results indicate that the proposed fault diagnosis model can effectively classify faults in different circuits and system components of nuclear power units into hierarchical categories. However, the fault dataset in this study was obtained from a simulator, which may introduce additional information due to parameter redundancy, thereby affecting the diagnostic performance of the model.

Railway Turnout Machines (RTMs) are mission-critical components of the railway transportation infrastructure, responsible for directing trains onto desired tracks. For safety assurance applications, especially in early-warning scenarios, RTM faults are expected to be detected as early as possible on a continuous 7x24 basis. However, limited emphasis has been placed on distributed model inference frameworks that can meet the inference latency and reliability requirements of such mission critical fault diagnosis systems. In this paper, an edge-cloud collaborative early-warning system is proposed to enable real-time and downtime-tolerant fault diagnosis of RTMs, providing a new paradigm for the deployment of models in safety-critical scenarios. Firstly, a modular fault diagnosis model is designed specifically for distributed deployment, which utilizes a hierarchical architecture consisting of the prior knowledge module, subordinate classifiers, and a fusion layer for enhanced accuracy and parallelism. Then, a cloud-edge collaborative framework leveraging pipeline parallelism, namely CEC-PA, is developed to minimize the overhead resulting from distributed task execution and context exchange by strategically partitioning and offloading model components across cloud and edge. Additionally, an election consensus mechanism is implemented within CEC-PA to ensure system robustness during coordinator node downtime. Comparative experiments and ablation studies are conducted to validate the effectiveness of the proposed distributed fault diagnosis approach. Our ensemble-based fault diagnosis model achieves a remarkable 97.4% accuracy on a real-world dataset collected by Nanjing Metro in Jiangsu Province, China. Meanwhile, CEC-PA demonstrates superior recovery proficiency during node disruptions and speed-up ranging from 1.98x to 7.93x in total inference time compared to its counterparts.

Deep learning models have created great opportunities for data-driven fault diagnosis but they require large amount of labeled failure data for training. In this paper, we propose to use a digital twin to support developing data-driven fault diagnosis model to reduce the amount of failure data used in the training process. The developed fault diagnosis models are also able to diagnose component-level failures based on system-level condition-monitoring data. The proposed framework is evaluated on a real-world robot system. The results showed that the deep learning model trained by digital twins is able to diagnose the locations and modes of 9 faults/failure from $4$ different motors. However, the performance of the model trained by a digital twin can still be improved, especially when the digital twin model has some discrepancy with the real system.

With the advancement of internet communication and telemedicine, people are increasingly turning to the web for various healthcare activities. With an ever-increasing number of diseases and symptoms, diagnosing patients becomes challenging. In this work, we build a diagnosis assistant to assist doctors, which identifies diseases based on patient-doctor interaction. During diagnosis, doctors utilize both symptomatology knowledge and diagnostic experience to identify diseases accurately and efficiently. Inspired by this, we investigate the role of medical knowledge in disease diagnosis through doctor-patient interaction. We propose a two-channel, knowledge-infused, discourse-aware disease diagnosis model (KI-DDI), where the first channel encodes patient-doctor communication using a transformer-based encoder, while the other creates an embedding of symptom-disease using a graph attention network (GAT). In the next stage, the conversation and knowledge graph embeddings are infused together and fed to a deep neural network for disease identification. Furthermore, we first develop an empathetic conversational medical corpus comprising conversations between patients and doctors, annotated with intent and symptoms information. The proposed model demonstrates a significant improvement over the existing state-of-the-art models, establishing the crucial roles of (a) a doctor's effort for additional symptom extraction (in addition to patient self-report) and (b) infusing medical knowledge in identifying diseases effectively. Many times, patients also show their medical conditions, which acts as crucial evidence in diagnosis. Therefore, integrating visual sensory information would represent an effective avenue for enhancing the capabilities of diagnostic assistants.

Zero-shot fault diagnosis (ZSFD) is capable of identifying unseen faults via predicting fault attributes labeled by human experts. We first recognize the demand of ZSFD to deal with continuous changes in industrial processes, i.e., the model's ability to adapt to new fault categories and attributes while avoiding forgetting the diagnosis ability learned previously. To overcome the issue that the existing ZSFD paradigm cannot learn from evolving streams of training data in industrial scenarios, the incremental ZSFD (IZSFD) paradigm is proposed for the first time, which incorporates category increment and attribute increment for both traditional ZSFD and generalized ZSFD paradigms. To achieve IZSFD, we present a broad-deep mixed anti-forgetting framework (BDMAFF) that aims to learn from new fault categories and attributes. To tackle the issue of forgetting, BDMAFF effectively accumulates previously acquired knowledge from two perspectives: features and attribute prototypes. The feature memory is established through a deep generative model that employs anti-forgetting training strategies, ensuring the generation quality of historical categories is supervised and maintained. The diagnosis model SEEs the UNSEEN faults with the help of generated samples from the generative model. The attribute prototype memory is established through a diagnosis model inspired by the broad learning system. Unlike traditional incremental learning algorithms, BDMAFF introduces a memory-driven iterative update strategy for the diagnosis model, which allows the model to learn new faults and attributes without requiring the storage of all historical training samples. The effectiveness of the proposed method is verified by a real hydraulic system and the Tennessee-Eastman benchmark process.

Cognitive diagnosis models have been widely used in different areas, especially intelligent education, to measure users' proficiency levels on knowledge concepts, based on which users can get personalized instructions. As the measurement is not always reliable due to the weak links of the models and data, the uncertainty of measurement also offers important information for decisions. However, the research on the uncertainty estimation lags behind that on advanced model structures for cognitive diagnosis. Existing approaches have limited efficiency and leave an academic blank for sophisticated models which have interaction function parameters (e.g., deep learning-based models). To address these problems, we propose a unified uncertainty estimation approach for a wide range of cognitive diagnosis models. Specifically, based on the idea of estimating the posterior distributions of cognitive diagnosis model parameters, we first provide a unified objective function for mini-batch based optimization that can be more efficiently applied to a wide range of models and large datasets. Then, we modify the reparameterization approach in order to adapt to parameters defined on different domains. Furthermore, we decompose the uncertainty of diagnostic parameters into data aspect and model aspect, which better explains the source of uncertainty. Extensive experiments demonstrate that our method is effective and can provide useful insights into the uncertainty of cognitive diagnosis.

Melanoma is a type of cancer that begins in the cells controlling the pigment of the skin, and it is often referred to as the most dangerous skin cancer. Diagnosing melanoma can be time-consuming, and a recent increase in melanoma incidents indicates a growing demand for a more efficient diagnostic process. This paper presents a pipeline for melanoma diagnostics, leveraging two convolutional neural networks, a diagnosis, and a prognosis model. The diagnostic model is responsible for localizing malignant patches across whole slide images and delivering a patient-level diagnosis as malignant or benign. Further, the prognosis model utilizes the diagnostic model's output to provide a patient-level prognosis as good or bad. The full pipeline has an F1 score of 0.79 when tested on data from the same distribution as it was trained on.

In-hospital patient outcome prediction is a major research area at the intersection of machine learning and medicine [Barfod et al., 2012, Taylor et al., 2016, Brajer et al., 2020, Naemi et al., 2021, Soffer et al., 2021, Wiesenfeld et al., 2022]. An important application of such models is'early' risk prediction - for example, using risk scores for triage [Raita et al., 2019, Klug et al., 2020]. Early prediction often requires calculating patient risk when primary diagnosis is still unknown or uncertain. We propose a method for incorporating uncertainty about diagnosis into mortality risk assessments in an interpretable and actionable way. We study the problem of all-cause in-hospital mortality prediction in the MIMIC-IV dataset [Johnson et al., 2023]. We find that a single model which pools all data and ignores diagnoses (we refer to this as the all-cause model or ACM) performs better at prediction than diagnosis-specific modeling. This increase in performance comes from the fact that the ACM has access to more data (so has lower variance) and that there is substantial transferrability in risk across diagnoses (so the ACM bias is not that high). We see this even more starkly by showing that a model trained only on out-of-diagnosis data can, due to this logic, predict risk within a diagnosis just as well as a model trained on that diagnosis only. While ACM are on average quite performant, we find that there are cases where they can fail.

Intelligent learning diagnosis is a critical engine of intelligent tutoring systems, which aims to estimate learners' current knowledge mastery status and predict their future learning performance. The significant challenge with traditional learning diagnosis methods is the inability to balance diagnostic accuracy and interpretability. Although the existing psychometric-based learning diagnosis methods provide some domain interpretation through cognitive parameters, they have insufficient modeling capability with a shallow structure for large-scale learning data. While the deep learning-based learning diagnosis methods have improved the accuracy of learning performance prediction, their inherent black-box properties lead to a lack of interpretability, making their results untrustworthy for educational applications. To settle the above problem, the proposed unified interpretable intelligent learning diagnosis (UIILD) framework, which benefits from the powerful representation learning ability of deep learning and the interpretability of psychometrics, achieves a better performance of learning prediction and provides interpretability from three aspects: cognitive parameters, learner-resource response network, and weights of self-attention mechanism. Within the proposed framework, this paper presents a two-channel learning diagnosis mechanism LDM-ID as well as a three-channel learning diagnosis mechanism LDM-HMI. Experiments on two real-world datasets and a simulation dataset show that our method has higher accuracy in predicting learners' performances compared with the state-of-the-art models, and can provide valuable educational interpretability for applications such as precise learning resource recommendation and personalized learning tutoring in intelligent tutoring systems.